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Beyond the budget silo approach: estimating health system sustainability for future dementia drugs

Opinion Paper
Aim of the study: to analyze the impact of a hypothetic disease-modifying drug (DMD) on the estimated costs of dementia sustained by the National H...
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Esketamine: the first glutamatergic drug for the management of treatment- resistant depression

Review
Intranasal esketamine has been recently approved by the American Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for tre...
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From Gut to Brain: a pas de deux between oleoylethanolamide and neuronal histamine

Review
Brain responses to feeding start before consumption, since seeing, smelling or just think about food may elicit exocrine and endocrine secretions i...
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Abdominal pain: mechanisms, therapies and experimental models

Review
Chronic or recurrent abdominal pain is the most prevalent gastrointestinal disorder, affecting 10% of the general population, including children an...
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State of the art on clinical trials of gene therapy in haemophilia

Review
Haemophilia A and B are rare inherited bleeding disorders, caused by deficiency or dysfunction .of the coagulation factors(F) VIII (haemophilia A) ...
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