Issues

Ultrasonic communication deficits in p50 KO mice and effect of maternal enrichment

M. Premoli, S. A. Bonini, A. Mastinu, G. Maccarinelli, G. Paiardi, F. Aria, M. Memo

Vol. 2 (No.1) 2020 April
Post-it In Pharmacology,
doi: 10.36118/pharmadvances.01.2020.17

Mice emit ultrasonic vocalizations (USVs) under different social conditions: pups maternal separation, juveniles play and adults mating and social investigation. The USVs measurement has become an important instrument for behavioral phenotyping in neurodevelopmental disorders (NDDs). Many studies have shown the fundamental role of maternal enrichment with long-term positive effects on brain and behavior in mouse models of NDDs. In this study, we wanted to investigate if mice lacking the NF-ĸB p50 subunit (p50 knock-out, KO) that are a mouse model of NDDs, had alterations in ultrasonic communication and if these calling patterns were influenced by maternal behavior.

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Table of Content: Vol. 2 (No.1) 2020 April

  1. Official Statement of the section of Clinical Pharmacology of the Italian Society of Pharmacology on the use of ACE- inhibitors or angiotensin receptor blockers in COVID-19 infection with commentary

    G. Trifirò 1,2, L. Berrino 3, M. Del Re 4, R. Bernardini 5, C. Chiamulera 6, A. D’Avolio 7, F. Scaglione 8, A. Capuano 9, E. Clementi 10, R. Danesi 4, L. Pani 11, A. Catapano 12, G. Racagni 12, on behalf of the Section of Clinical Pharmacology of Italian Society of Pharmacology
    Letter to the Editor, 1-5
    doi: 10.36118/pharmadvances.01.2020.01
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  2. Official Statement of the section of Clinical Pharmacology of Italian Society of Pharmacology on Non-steroidal anti-inflammatory drugs (NSAIDs) and the increased risk of complications during infections with commentary

    A. Capuano 1, F. Scaglione 2, L. Berrino 3, M. Del Re 4, R. Bernardini 5, C. Chiamulera 6, A. D’Avolio 7, G. Trifirò 8,9, E. Clementi 10, R. Danesi 4, L. Pani 11, G. Racagni 12 on behalf of the section of Clinical Pharmacology of Italian Society of Pharmacology
    Letter to the Editor, 6-10
    doi: 10.36118/pharmadvances.01.2020.03
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  3. Angiotensin-converting enzyme-2 (ACE2): New opportunity or red herring?

    M. Vicenzi 1,2, A. Corsini 3,4, M. Ruscica 3
    Short Article, 11-13
    doi: 10.36118/pharmadvances.01.2020.05
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  4. The contribution of the clinical laboratory to the new medicine paradigm

    L. Mariani, D. Pedrazzini
    Research Article, 14-18
    doi: 10.36118/pharmadvances.01.2020.06
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  5. Independent Research in Italy

    G. Corbellini
    Opinion Paper, 19-30
    doi: 10.36118/pharmadvances.01.2020.07
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  6. Treatment of chronic pain in Italy: therapeutic appropriacy of opioids and fear of addiction. The situation in Italy vs. USA

    D. Fornasari 1, G. Gerra 2, S. Maione 3, G. Mannaioni 4, A. Mugelli 5, D. Parolaro 6, P. Romualdi 7, P. Sacerdote 8
    Research Article, 31-40
    doi: 10.36118/pharmadvances.01.2020.08
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  7. Herb and spice mediated interactions in oncologic patients treated with chemotherapy

    F. Turco, A. Elio Sprio, I. Bertaggia, T. Armando, S. Storto, S. Allegra, S. De Francia, M. V. Mussa
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.10
    Full text PDF

  8. Vaccines Safety in Children and in General Population: A Pharmacovigilance Study on Adverse Events Following Anti-Infective Vaccination in Italy

    N. Lombardi, G. Crescioli, A. Bettiol, M. Tuccori, M Rossi, R. Bonaiuti, C. Ravaldi, M. Levi, A. Mugelli, S. Ricci, F. Lippi, C. Azzari, P. Bonanni, A. Vannacci
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.11
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  9. Factors influencing the antiplatelet therapy in patients requiring vascular surgery

    C. Sellitto, V. Conti Valeria, V. Manzo Valentina, T. Iannaccone, M. Costantino, M. Torsiello, G. Di Fiore, G. Accarino, G. Nicolella, G. Corbi, A. Filippelli
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.12
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  10. Effect of Lactobacillus farciminis supplementation in preventing LPS-induced hippocampal neuroinflammation, in mice

    C. Petrella, G. Strimpakos, F. De Santa, M. Fiore, D. Mora, S. Arioli, S. Farioli-Vecchioli
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.13
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  11. Role of maternal immune activation in neurodevelopment disorders and possible pharmacological treatment

    F. Aria, A. Mastinu, G. Maccarinelli, M. Premoli, M. Memo, S. A. Bonini
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.15
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  12. The novel fentanyl-analog “Acrylofentanyl” impairs motor, sensorimotor and cardiovascular functions in mice.

    S. Bilel, R. Arfè, M. Tirri, C. Trapella, P. Frisoni, M. Neri, M. Marti
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.14
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  13. A new HPLC-UV method compared with HPLC-MS for daptomycin levels in human plasma samples

    G. Luci, F. Cucchiara, M. Lastella, L. Ciofi, R. Danesi, A. Di Paolo
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.16
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  14. Ultrasonic communication deficits in p50 KO mice and effect of maternal enrichment

    M. Premoli, S. A. Bonini, A. Mastinu, G. Maccarinelli, G. Paiardi, F. Aria, M. Memo
    Post-it In Pharmacology,
    doi: 10.36118/pharmadvances.01.2020.17
    Full text PDF
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